Free Foreign Pharmacy Graduate Equivalency Examination Exam FPGEE Exam Practice Test

Gamma aminobutyric acid (GAB

• is: I the major inhibitory neurotransmitter in the brain II found primarily in interneurons III synthesized from glycine
• I only
• III only
• I and II only
• II and III only
• I, II and III

Condition characterized by a reversible form of airflow obstruction is known as:

• Aneurism
• Emphesema
• Embolism
• Cirrhose
• Jaundice

Drug that inhibits xanthine oxidase and affect the metabolism of 6-mercaptopurine:

• Sulfinpyrazone
• Allopurinol
• Penicillamine
• Purinethol
• Celecoxib

Characteristics of GOUT, a group of disorders of purine and pyrimidine metabolism may include:I- Hereditary metabolite disease marked by inflammation of the jointsII- The joint inflammation is caused by precipitation of uric acid crystalsIII- It is a type osteoporosis

• I only
• III only
• I and II only
• II and III only
• All are correct

False statement regarding vitamin D3 metabolism include:

• Vitamin C facilitates absorption of vitamin D3 in the liver
• Hydroxylation of D3 is in kidney
• Hydroxylation of is D3 in the liver
• Parathyroid hormone activate metabolism of vitamin D3 in the kidney
• Skin activates synthesis of vitamin D3 by sunlight

Select the drug whose major metabolites have therapeutically significant pharmacological activity:

• oxazepam
• nitrazepam
• diazepam
• triazolam
• clonazepam

Class of cocaine is:

• Retinoids
• Anti-asthmatic agents
• Autonomic nervous system drugs
• Loop diuretics
• Antiarrhythmic agents

Correct statement regarding the mechanism of action of Vancomycin may include:

• Inhibit release of tRNA bound to peptyl site after peptide bond formation
• Inhibit peptide bound formation between acylaminoacids bound to the peptyl and acceptor site
• Inhibit stage II of cell wall synthesis preventing polymerization of the linear peptideoglycan
• Inhibit DNA gyrase in the bacteria
• Bind to ergosterol from pores resulting in linkage of cellular

The codon sequence Adenine-Guanine-Cytosine-Uracil is seen inI- RNAsII- DNAsIII- Both DNAs and RNAs

• I only
• III only
• I and II only
• II and III only
• All are correct

Protein disnaturation may happen due to:

• Exposure to air
• Shaking
• Increase in temperature
• Chemical reagents
• All are correct